Instead of speaking to his mistress directly as he usually does in the "dark lady" sonnets, the speaker is revealing the falseness and foulness of her character, as he speaks directly to "Love." But he is employing the term, "Love," euphemistically; his drama depicting the relationship between his heart and his eyes demonstrates that he is, in reality, addressing "lust."
The speaker appends his first question, as he often does in this kind of musing. He wishes to know what "Love" does to him to make his eyes not see appropriately. He labels "Love" the "blind fool," as he makes it clear that he is, indeed, the "blind fool" because of "lust." He cannot comprehend that his eyes would betray him; he feels that he is aware of what beauty is, yet when he chances to meet this particular woman, he always manages to become confused by her physical beauty.